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Polymastiamides B-F, novel steroid/amino acid conjugates isolated from the Norwegian marine sponge Polymastia boletiformis

TitlePolymastiamides B-F, novel steroid/amino acid conjugates isolated from the Norwegian marine sponge Polymastia boletiformis
Publication TypeJournal Article
Year of Publication1996
AuthorsKong, FM, Andersen, RJ
JournalJournal of Natural Products
Volume59
Pagination379-385
Date PublishedApr
Type of ArticleArticle
ISBN Number0163-3864
Abstract

The structures of polymastiamides B-F (2-6), five new steroid/amino acid conjugates isolated from the Norwegian marine sponge Polymastia boletiformis, have been solved by spectroscopic analysis of their desulfated methyl esters 8-12, respectively. Polymastiamides were found to undergo double-bond migration during treatment with MeOH/HCl to give the Delta(14,15) artifacts 13 to 16. A C-ring benzenoid artifact 17 was also obtained from the methylation reaction.

URL<Go to ISI>://A1996UR60100008