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Progress towards the Synthesis of Sordarin and its Analogs.

TitleProgress towards the Synthesis of Sordarin and its Analogs.
Publication TypeJournal Article
Year of Publication2010
AuthorsLiang, H, Ciufolini, MA
JournalOrganic Preparations and Procedures International
Volume42
Pagination111 - 132
Date Published2010///
ISBN Number0030-4948
Keywordsreview sordarin synthesis synthon glycoside terpenoid
Abstract

A review with refs. This work led to building blocks that may be useful for the prepn. of analogs of sordarin exhibiting a modified terpenoid core. Congeners of sordarin constructed from these intermediates should enable a detailed SAR investigation of the terpenoid core. This knowledge is likely to prove essential to the development of new antifungal agents based on a sordarin motif. Reload. [on SciFinder(R)]