Title | A sequential C-N, C-C bond-forming reaction: Direct synthesis of alpha-amino acids from terminal alkynes |
Publication Type | Journal Article |
Year of Publication | 2006 |
Authors | Lee, AV, Schafer, LL |
Journal | Synlett |
Pagination | 2973-2976 |
Date Published | Nov |
ISBN Number | 0936-5214 |
Abstract | Catalytic hydroamination is combined with the Strecker reaction to yield a one-pot synthesis of alpha-cyanoamines from terminal alkynes. This methodology is further applied to the synthesis of alpha-amino acids and alpha-amino esters. |
URL | <Go to ISI>://000243619600017 |
