Title | Studies toward the synthesis of contignasterol: Functionalization of the steroidal A,B ring system |
Publication Type | Journal Article |
Year of Publication | 2002 |
Authors | Rogers, C, Shen, YP, Burgoyne, D, Piers, E |
Journal | Synthetic Communications |
Volume | 32 |
Pagination | 2991-3002 |
Type of Article | Article |
ISBN Number | 0039-7911 |
Keywords | EPOXIDATION, lithium, ring opening, stereoselective reduction, steroid |
Abstract | The synthesis of androstane-3alpha,4beta,6alpha,7beta-tetrol-17-one (2), a potentially key intermediate for the preparation of contignasterol (1), was achieved by functionalization of the A,B-ring portion or the readily available androst-4-ene-3,17-dione (3). |
URL | <Go to ISI>://000178124600011 |