Title | TERPENOID METABOLITES FROM SKIN EXTRACTS OF 4 SRI-LANKAN NUDIBRANCHS IN THE GENUS CHROMODORIS |
Publication Type | Journal Article |
Year of Publication | 1991 |
Authors | De Silva, ED, Morris, SA, Miao, SC, Dumdei, E, Andersen, RJ |
Journal | Journal of Natural Products |
Volume | 54 |
Pagination | 993-997 |
Date Published | Jul-Aug |
Type of Article | Article |
ISBN Number | 0163-3864 |
Keywords | CONSTITUENTS, REARRANGED SPONGIAN DITERPENES |
Abstract | The skin extracts of four species of Sri Lankan dorid nudibranchs belonging to the genus Chromodoris have been found to contain diterpenoids. Extracts of Chromodoris gleneii contained dendrillolide A [1], 12-desacetoxyshahamin C [2], and shahamin K [3]; extracts of Chromodoris geminus contained 12-beta, 15-alpha, 16-alpha-triacetoxyspongian [4], 6-alpha, 15-alpha, 16-alpha-triacetoxyspongian [5], and 6-alpha, 12-beta, 15-alpha, 16-alpha-tetraacetoxyspongian [6]; extracts of Chromodoris annulata contained shahamin F [7]; and extracts of Chromodoris inopinata contained aplyroseol 2 [8], the gamma-lactone 9, and spongian-16-one [10]. Compounds 3, 5, and 6 are new diterpenoid metabolites. The remaining diterpenoids 1, 2, 4, and 7-10 have been previously isolated from marine sponges or other nudibranchs. |
URL | <Go to ISI>://A1991GF52600011 |