Activation of Small Molecules on Al(I) and Ga(I) Carbenoids: from Bond Cleavage to Coupling Reactions

Activation of small molecules by low-valent main group compounds is a hot topic,¹ of which the bond cleavage by carbenoids, electronic analogues of carbene, is the most common.² The NacNac-supported Al(I) and Ga(I) compounds NacNacM have been in the focus of several groups, including ours. In this talk we shall review the results of the past decade of research³ and highlight the increasing complication of reactivity, progressing from bond activation to multicomponent reactions and coupling.⁴ 

1.    (a) Power, P. P. Nature 2010, 464, 171. (b) Weetman C.; Inoue, S. ChemCatChem 2018, 10, 4213.
2.    Nikonov, G. I.; Chu, T. Chem. Rev. 2018, 118, 3608.
3.    Nikonov, G. I. et al. J. Am. Chem. Soc. 2014, 136, 9195; Angew. Chem. Int. Ed. 2016, 55, 13306; Inorg. Chem. 2017, 56, 5993; J. Am. Chem.Soc. 2017, 139, 8804;
4.    Nikonov, G. I. et al. Angew. Chem. Int. Ed. 2019, 58, 18102; Chem. Eur. J. 2020, 26, 206; Angew. Chem. Int. Ed. 2020, 59, 16281; Chem. Eur. J. 2021, 27, 5730; Chem. Comm., 2022, 58, 6946.