Dr. Perrin and his group have been highlighted in Chemical and Engineering News for their synthesis of α-amanitin, a bicyclic octapeptide produced by the death-cap mushroom, and one of the deadliest known peptide toxins. Now that they have a synthetic route for making α-amanitin, they plan to use it to make antibody-drug conjugates and to study the chemical biology of the toxin.
Read more: https://cen.acs.org/articles/96/i14/Death-cap-mushroom-toxin-synthesized.html?h=724455988