Title | Vanadium complexes as insulin mimetic agents: Coordination chemistry and in vivo studies of oxovanadium(IV) and dioxovanadate(V) complexes formed from naturally occurring chelating oxazolinate, thiazolinate, or picolinate units |
Publication Type | Journal Article |
Year of Publication | 1999 |
Authors | Melchior, M, Thompson, KH, Jong, JM, Rettig, SJ, Shuter, E, Yuen, VG, Zhou, Y, McNeill, JH, Orvig, C |
Journal | Inorganic Chemistry |
Volume | 38 |
Pagination | 2288-2293 |
Date Published | May |
Type of Article | Article |
ISBN Number | 0020-1669 |
Keywords | BIS(MALTOLATO)OXOVANADIUM(IV), BMOV, CRYSTAL-STRUCTURE, DIABETIC RATS, GLUCOSE, NMR, SIDEROPHORE, SULFATE, SYSTEM, VANADATE |
Abstract | {The synthesis and characterization of four complexes containing naturally occurring binding groups are reported: VO(pic)(2). H2O (Hpic = picolinic or pyridine-2-carboxylic acid), NH4[VO2(pic)(2)]. 2H(2)O, VO(oz)(2) (Hoz = 2-(2’- hydroxyphenyl)-2-oxazoline), and VO(thoz)(2) (Hthoz = 2-(2’-hydroxyphenyl)-2-thiazoline). The X-ray structures of [NH4[VO2(pic)(2)]. 2H(2)O, VO(oz)(2), and VO(thoz)(2) have been determined. Crystals of NH4[VO2(pic)(2)]. 2H(2)O (C12H12N3O6V . 2H(2)O) are monoclinic, space group Cc, a 10.347(2) Angstrom |
URL | <Go to ISI>://000080459200009 |
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