| Title | Diterpenoids from cultured Erythropodium caribaeorum |
| Publication Type | Journal Article |
| Year of Publication | 2002 |
| Authors | Taglialatela-Scafati, O, Deo-Jangra, U, Campbell, M, Roberge, M, Andersen, RJ |
| Journal | Organic Letters |
| Volume | 4 |
| Pagination | 4085-4088 |
| Date Published | Nov |
| Type of Article | Article |
| ISBN Number | 1523-7060 |
| Keywords | ELEUTHEROBIN, ERYTHROLIDES, HALICHONDRIN-B, PHARMACOPHORE, REARRANGEMENT |
| Abstract | [GRAPHICS] The known antimitotic agent eleutherobin and the briarane diterpenoids erythrolides A and B have been isolated from cultured specimens of Erythropodium caribaeorum in amounts,comparable to those reported from wild-harvested reef animals. The novel diterpenoid aquariolide A, having an unprecedented highly-rearranged carbon skeleton (named aquariane), has also been found. The aquariane skeleton can be formally derived from the briarane-skeleton by sequential di-pi-methane and vinyl-cyclopropane rearrangements. |
| URL | <Go to ISI>://000179173700025 |
