| Title | G(boolean AND)C quartet - A DNA-inspired Janus-GC heterocycle: Synthesis, structural analysis, and self-organization |
| Publication Type | Journal Article |
| Year of Publication | 2008 |
| Authors | Asadi, A, Patrick, BO, Perrin, DM |
| Journal | Journal of the American Chemical Society |
| Volume | 130 |
| Pagination | 12860-+ |
| Date Published | Oct |
| Type of Article | Article |
| ISBN Number | 0002-7863 |
| Keywords | BASE, CHEMISTRY, COMPLEXES, DERIVATIVES, FOLIC-ACID SALTS, HELICAL ROSETTE NANOTUBES, HYDROGEN-BONDED NETWORKS, MOLECULAR TECTONICS, RECOGNITION, solid-state structures |
| Abstract | In this communication we disclose the synthesis and characterization of a DNA-inspired self-complementary heterocycle that contains AAD-DAA H-bond acceptor/donor patterns. Whereas in the past such AAD-DAA self-complementarity has given rise to trimeric and hexameric rosettes, we now demonstrate that the same H-bonding scheme, when properly arrayed, can be used to program a tetrameric rosette, which unlike a G-quartet requires no metal binding or peripheral components for p reorganization. Of note, we exploit both 2D-NOESY and DOSY H-1 NMR to substantiate the tetrameric stoichiometry in this noncovalent rosette comprising 12 H-bonds. |
| URL | <Go to ISI>://000259553700012 |
