Date:
Thursday, November 28, 2024 - 15:30 to 16:30
Speaker:
Dr. Frederick West
Affiliation:
Department of Chemistry, University of Alberta
Event Category:
Special Seminar
Host:
Dr. Glenn Sammis
Location:
Chemistry D200
Abstract:
Installation of an allene unit into a small ring (≤7-membered) imparts high reactivity due the bond angle distortion imposed on this normally linear moiety. An example of this unusual reactivity is the ready entry of cyclic allenes into pericyclic reactions that would normally require substantial energy input to overcome activation energies. This talk will address methods for generating these transient intermediates, their application in synthetically useful transformations, and efforts to adapt this chemistry to enantioselective synthesis.